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Moldable autogenous tooth bone graft (M-AutoBT) in sinus-related defects with implant: 3 case reports of long-term follow up

Journal of Dental Implant Research 2019³â 38±Ç 1È£ p.24 ~ 29
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±¸Á¤±Í ( Ku Jeong-Kui ) - Armed Forces Capital Hospital Department of Oral and Maxillofacial Surgery
ÀÌÁ¤±Ù ( Lee Jeong-Keun ) - Ajou University Medical Center Department of Oral and Maxillofacial Surgery
¹Îö±â ( Min Chul-Gi ) - Seoul Highan Dental Clinic
±èÀ¯¹Ì ( Kim Yu-Mi ) - Korea Tooth Bank
¾öÀοõ ( Um In-Woong ) - Korea Tooth Bank

Abstract


Purpose: A moldable autogenous tooth bone graft material (M-AutoBT, Korea Tooth Bank, Seoul, Korea), which is made from demineralized dentin matrix (DDM) powder and hydroxypropylmethyl cellulose (HPMC), is sticky and moldable, making it easy to handle and allowing it to fit into large defects. This case report evaluates the remodeling capacity and long-term stability of moldable demineralized dentin matrix (M-AutoBT) in three sinus-related cases first reported in 2015.

Materials and Methods: M-AutoBT, which is made from demineralized dentin matrix (DDM) powder and hydroxypropylmethyl cellulose (HPMC), is a sticky and moldable to fit easily into large defects. Cone-beam computerized tomography was used to evaluate the changes in M-AutoBT around the dental implant in the sinus area from immediately after surgery to the final follow-up (2, 3, and 5 years).

Results: In all three cases, regardless of the sinus graft procedure, M-AutoBT showed successful bone formation around the dental implant and maintained its volume and the shape of the cortico-cancellous bone without marginal bone loss during long-term prosthetic loading.

Conclusions: HPMC is a base material that contains AutoBT powders and is a moldable and injectable bone substitute material (M-AutoBT) that can fit into a range of defects. M-AutoBT has osteoinductive and osteoconductive capacities. The present study suggests that bone-forming capacity and long term stability of M-AutoBT are similar to the conventional AutoBT, regardless of the characteristics of the defect and the different pathways of the blood supply. Therefore, HPMC powder might be an effective base material for conventional AutoBT powder.

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Bone; Dentin; Bone substitute; Demineralized dentin matrix (DDM)

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